CDH23 anticorps (Internal Region)

N° du produit ABIN375183

Détail du produit anti-CDH23 anticorps

Antigène: CDH23 (Cadherin 23 (CDH23))

Épitope: Internal Region

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp CDH23 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to CDH23 / USH1D.

Purification: Affinity chromatography

Immunogène: Peptide with sequence C-YNISLYENVTVGTS, from the internal region of the protein sequence

Information d'application

Indications d'application: Peptide ELISA: 1/1000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CDH23

Antigène: CDH23 (Cadherin 23 (CDH23))

Autre désignation: Cadherin-23 (CDH23 Produits)

Synonymes: anticorps 4930542A03Rik, anticorps USH1D, anticorps ahl, anticorps ahl1, anticorps bob, anticorps bus, anticorps mdfw, anticorps nmf112, anticorps nmf181, anticorps nmf252, anticorps sals, anticorps v, anticorps CDHR23, anticorps W, anticorps cadherin 23 (otocadherin), anticorps cadherin related 23, anticorps cadherin-related 23, anticorps Cdh23, anticorps CDH23

Sujet: Cadherin like 23 (or Cadherin 23) is, like other members of the cadherin family, a calcium-dependent cell adhesion glycoprotein that preferentially interacts with itself in connecting cells. It is a single pass type I membrane protein that contains 27 cadherin domains. Cadherin like 23 is expressed in the neurosensory epithelium, where it is thought to be involved in stereocilia organisation and hair bundle formation. Defects in the gene encoding Cadherin like 23 are a cause of Usher syndrome, which is characterised by profound congenital sensorineural deafness and eventual blindness. Mutations in this gene are also a cause of non-syndromic sensorineural deafness autosomal recessive type 12 (DFNB12). Cadherin like 23 has also been associated with age-related hearing loss.Synonyms: CDH23, KIAA1774, KIAA1812

ID gène: 64072

NCBI Accession: NP_001165401

UniProt: Q9H251

Pathways: Sensory Perception of Sound