CNTF Receptor alpha anticorps (Internal Region)

N° du produit ABIN375185

L’anticorps anti-CNTF Receptor alpha Polyclonal Chèvre est utilisé pour la détection de CNTF Receptor alpha dans des échantillons de Souris. Il a été validé pour WB et EIA.

Aperçu rapide pour CNTF Receptor alpha anticorps (Internal Region) (ABIN375185)

Antigène: CNTF Receptor alpha (CNTFR) (Ciliary Neurotrophic Factor Receptor (CNTFR))

Reactivité: Souris

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp CNTF Receptor alpha est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-CNTF Receptor alpha anticorps

Épitope: Internal Region

Specificité: This antibody reacts to CNTFR.

Réactivité croisée (Details): Species reactivity (expected):Human, Rat, Canine.
Species reactivity (tested):Mouse.

Purification: Affinity chromatography

Immunogène: Peptide with sequence CRSNTYPKGFY, from the internal region of the protein sequence

Information d'application

Indications d'application: Peptide ELISA: 1/16000. Western Blot: 0.3 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CNTF Receptor alpha

Antigène: CNTF Receptor alpha (CNTFR) (Ciliary Neurotrophic Factor Receptor (CNTFR))

Autre désignation: CNTFR

Sujet: CNTF Receptor alpha is a receptor belonging to the cytokine superfamily of receptors. Along with LIFR and gp130, CNTF Receptor alpha forms the heterotrimeric CNTF receptor complex. The receptor is attached to the membrane by a glycosyl-phosphatidylinositol linkage and contains an immunoglobulin-like C2-type domain and a fibronectin type-III domain. During signal transduction, CNTF first binds to CNTF Recepror alpha, and this permits the recruitment of gp130 and LIFR beta to form the tripartite receptor complex. Signal transduction stimulates gene expression, cell survival or differentiation in a variety of neuronal cell types. Alternative splicing has been observed at this locus and two variants, both encoding the same protein, have been identified.Synonyms: CNTFR, CNTFR alpha, Ciliary neurotrophic factor receptor alpha

ID gène: 12804

NCBI Accession: NP_001129528

UniProt: O88507

Pathways: Signalistation JAK/STAT, Feeding Behaviour