MARK2 anticorps (Internal Region)

N° du produit ABIN375213

Cet anticorps anti-MARK2 Polyclonal Chèvre (ABIN375213) détecte spécifiquement MARK2 dans WB et EIA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour MARK2 anticorps (Internal Region) (ABIN375213)

Antigène: MARK2 (MAP/microtubule Affinity-Regulating Kinase 2 (MARK2))

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp MARK2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-MARK2 anticorps

Épitope: Internal Region

Specificité: This antibdoy reacts to MARK2.

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, Bovine.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogène: Peptide with sequence C-QNGKDSTAPQR, from the internal region of the protein sequence

Information d'application

Indications d'application: ELISA: 1/16000. Western Blot: 0.3 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur MARK2

Antigène: MARK2 (MAP/microtubule Affinity-Regulating Kinase 2 (MARK2))

Autre désignation: MARK2

Sujet: MARK2 refers to MAP/microtubule affinity-regulating kinase 2 isoform a [Homo sapiens]. EMK (ELKL Motif Kinase) is a small family of ser/thr protein kinases involved in the control of cell polarity, microtubule stability and cancer. Several cDNA clones have been isolated that encoded two isoforms of the human ser/thr protein kinase EMK1 called MARK2. These isoforms were characterized by the presence of a 162-bp alternative exon that gave rise to two forms, one containing the exon and the other one lacking it. Both forms were found to be coexpressed in a number of selected cell lines and tissue samples. Human MARK2 was shown to be encoded by a single mRNA ubiquitously expressed. This transcription variant includes the alternative exon in the coding region and therefore codes for a longer protein. Multiple splice variants exist for this protein. Role in epithelial morphogenesis. Modulates the developmental decision to build a columnar versus a hepatic epithelial cell apparently by promoting a switch from a direct to a transcytotic mode of apical protein delivery. Essential for the asymmetric development of membrane domains of polarized epithelial cells.Synonyms: 2, ELKL motif kinase, EMK1, MAP/microtubule affinity-regulating kinase, MARK2, PAR1 homolog, Serine/threonine-protein kinase

ID gène: 2011

NCBI Accession: NP_001034558

UniProt: Q7KZI7

Pathways: SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2