GPI anticorps (pSer185)

N° du produit ABIN375349

Cet anticorps Lapin Polyclonal détecte spécifiquement GPI dans WB, ELISA et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour GPI anticorps (pSer185) (ABIN375349)

Antigène: GPI (Glucose-6-Phosphate Isomerase (GPI))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GPI est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-GPI anticorps

Épitope: pSer185

Specificité: Reacts with human 65 kDa GPI protein with a phosphoserine at position 185

Réactivité croisée (Details): Do not cross react with non-phospho GPI protein.

Purification: Antiserum

Immunogène: Synthetic peptide derived from human GPI containing a phosphoserine at position 185

Isotype: IgG

Information d'application

Indications d'application:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
- IHC : 1/200 to 1/1 000 - WB : 1/500 to 1/5 000

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Stock: 4 °C/-20 °C

Stockage commentaire: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Date de péremption: 24 months

Détails sur GPI

Antigène: GPI (Glucose-6-Phosphate Isomerase (GPI))

Sujet: Besides it's role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons. Phosphorylation at Ser-185 by CK2 has been shown to decrease enzymatic activity and may contribute to secretion by a non-classical secretory pathway.

UniProt: P06744