VPS39 anticorps

N° du produit ABIN375361

Détail du produit anti-VPS39 anticorps

Antigène: VPS39 (Vacuolar Protein Sorting 39 Homolog (VPS39))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VPS39 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: Reacts with human VPS39 102 kDa protein

Réactivité croisée: Souris

Réactivité croisée (Details): Cross reacts with mouse and other species.

Purification: Antiserum

Immunogène: Synthetic peptide derived from an internal domain of human Vam6 protein

Isotype: IgG

Information d'application

Indications d'application:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
- IHC : 1/50 to 1/500 - WB : 1/500 to 1/2 000

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Stock: 4 °C/-20 °C

Stockage commentaire: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Date de péremption: 24 months

Détails sur VPS39

Antigène: VPS39 (Vacuolar Protein Sorting 39 Homolog (VPS39))

Autre désignation: Vam6/Vps39-Like Protein (VPS39) (VPS39 Produits)

Synonymes: anticorps lbk, anticorps vam6, anticorps DKFZp469J2314, anticorps A230065P22Rik, anticorps AW743070, anticorps Vam6, anticorps Vam6P, anticorps mVam6, anticorps TLP, anticorps VAM6, anticorps hVam6p, anticorps VPS39, HOPS complex subunit, anticorps vacuolar protein sorting 39 homolog (S. cerevisiae), anticorps vam6/Vps39-like protein, anticorps vacuolar protein sorting 39, anticorps VPS39 HOPS complex subunit, anticorps VPS39, anticorps vps39, anticorps LOC100196283, anticorps NAEGRDRAFT_59276, anticorps Vps39

Sujet: May play a role in clustering and fusion of late endosomes and lysosomes. Regulator of TGF-beta/activin signaling, inhibiting SMAD3- and activating SMAD2-dependent transcription. Acts by interfering with SMAD3/SMAD4 complex formation, this would lead to inhibition of SMAD3-dependent transcription and relieve SMAD3 inhibition of SMAD2-dependent promoters, thus increasing SMAD2-dependent transcription.

UniProt: Q96JC1

Pathways: SARS-CoV-2 Protein Interactome