ITGAL anticorps

N° du produit ABIN375486

Cet anticorps anti-ITGAL est un anticorps Souris Monoclonal détectant ITGAL dans FACS, IP et IHC. Adapté pour Humain. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour ITGAL anticorps (ABIN375486)

Antigène: ITGAL (Integrin alpha-L (ITGAL))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ITGAL est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC)

Clone: 38

Détail du produit anti-ITGAL anticorps

Attributs du produit: The antibody detects: Human CD11a (LFA-1 α )
To insure lot to lot consistency, each batch of product is tested by flow cytometry to conform with the characteristics of a standard reference reagent.

Purification: Purified

niveau d'endotoxine: Low Endotoxin

Isotype: IgG2a

Information d'application

Indications d'application: Working Dilution:
<= 1 µg/10^6 cells
Representative data are included in this product insert.

Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

Commentaires:

Blocking studies, cell adhesion, cytotoxicity

Volume d'échantillon: 1 mL

Restrictions: For Research Use only

Stockage

Agent conservateur: Azide free

Conseil sur la manipulation: Each reagent is stable for the period shown on the bottle label if stored as directed.

Stock: -20 °C

Stockage commentaire: Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt.

Références pour anticorps anti-ITGAL (ABIN375486)

Venet, Ribeiro, Décembre, Bellomo, Joshi, Nuovo, Villard, Cluet, Perret, Pescamona, Paidassi, Walzer, Allatif, Belot, Trouillet-Assant, Ricci, Dreux: "Severe COVID-19 patients have impaired plasmacytoid dendritic cell-mediated control of SARS-CoV-2." dans: Nature communications, Vol. 14, Issue 1, pp. 694, (2023) (PubMed).

Détails sur ITGAL

Antigène: ITGAL (Integrin alpha-L (ITGAL))

Autre désignation: CD11a/LFA-1a

Sujet: CD11a, also known as leukocyte function-associated antigen-1 (LFA-1 α ), represents the 180 kDa integrin α L subunit which combines with the CD18 β 2 integrin subunit to form the α L β 2 integrin heterodimer. It is expressed on lymphocytes, granulocytes, monocytes, and macrophages and is upregulated on activated T cells. CD11a/LFA-1 α mediates adhesion of lymphocytes to vascular endothelium and is involved in costimulation.

Pathways: Activated T Cell Proliferation, Integrin Complex