CD8 alpha anticorps

N° du produit ABIN375493

Cet anticorps Rat Monoclonal détecte spécifiquement CD8 alpha dans FACS, IP, ICC, IHC (fro), BR et Dep. Il présente une réactivité avec des échantillons de Souris.

Aperçu rapide pour CD8 alpha anticorps (ABIN375493)

Antigène: CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CD8 alpha est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Blocking Reagent (BR), Depletion (Dep)

Clone: 53-6-7

Détail du produit anti-CD8 alpha anticorps

Fonction: Rat Anti-Mouse CD8α-LE/AF

Specificité: Mouse CD8α, Mr 32-34 kDa

Attributs du produit: Low Endotoxin/Azide Free Anti-Mouse CD8 alpha antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, immunoprecipitation, depletion, and blocking assays.

niveau d'endotoxine: Low Endotoxin

Immunogène: Spleen cells or thymocyte membranes

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Phosphate buffered saline, pH 7.4

Agent conservateur: Azide free

Conseil sur la manipulation: Each reagent is stable for the period shown on the bottle label if stored as directed.

Stock: 4 °C

Stockage commentaire: 2-8°C

Détails sur CD8 alpha

Antigène: CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Autre désignation: CD8alpha

Sujet: In the mouse, CD8 exists in two forms: (i) a CD8 heterodimer composed of an α chain (CD8 α /Lyt-2) and a β chain (CD8 β /Lyt-3), and (ii) a homodimer of two α chains. The heterodimer is found on the surface of essentially all thymocytes and the 'suppressor/cytotoxic' subpopulation of mature T lymphocytes. Subsets of intestinal intraepithelial lymphocytes express CD8 α without CD8 β. It has been suggested that CD8 + β - T cells mature extrathymically, while development of the CD8 α + β + population of T cells is thymus-dependent. CD8 acts as a coreceptor with MHC Class I-restricted T cell receptors in antigen recognition and positive selection of MHC class I-restricted CD8 + T cells

ID gène: 12525

UniProt: P01731

Pathways: TCR Signaling