CD33 anticorps
Aperçu rapide pour CD33 anticorps (ABIN376397)
Antigène
Voir toutes CD33 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Mouse Anti-Human CD33-LE/AF
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Specificité
- Human CD33, Mr 67 kDa
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Attributs du produit
- Low Endotoxin/Azide Free Anti-Human CD33 antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, immunoprecipitation, and blocking assays.
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niveau d'endotoxine
- Low Endotoxin
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Isotype
- IgG1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Phosphate buffered saline, pH 7.4
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Agent conservateur
- Azide free
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Conseil sur la manipulation
- Each reagent is stable for the period shown on the bottle label if stored as directed.
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Stock
- 4 °C
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Stockage commentaire
- 2-8°C
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- CD33
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Autre désignation
- CD33
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Sujet
- CD33 is a 67 kDa type I transmembrane glycoprotein and a member of the sialoadhesin family of cell surface receptors. It is absent from pluripotent stem cells but appears on myelomonocytic precursors after CD34. It then continues to be expressed on both the myeloid and monocyte lineages, although it is absent on granulocytes. While it has been reported that CD33 can function as a sialic acid-dependent cell adhesion molecule, cells expressing CD33 require desialylation before they can bind cells bearing the appropriate sialoglycoconjugates. This suggests that inhibitory cis interactions may regulate or block any adhesion function.
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ID gène
- 945
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UniProt
- P20138
Antigène
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