MSH6 anticorps
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- Antigène Voir toutes MSH6 Anticorps
- MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
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Reactivité
- Humain, Souris, Rat, Chien
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp MSH6 est non-conjugé
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Application
- Western Blotting (WB), Immunoprecipitation (IP)
- Specificité
- MSH6 is a heterodimer of MSH2 and binds to DNA containing G/T mismatches. The MSH2-MSH6 complex recognizes a single-based mispair insertion/deletion loop. An alteration of microsatellite repeats is the result of slippage owing to strand misalignment during DNA replication and is referred to as microsatellite instability (MSI). These defects in DNA repair pathways have been related human carcinogenesis. Studies have shown the mutations of MLH-1, MSH2 and MSH6 genes contribute to the development of sporadic colorectal carcinoma. The repair of mismatch DNA is essential to maintaining the integrity of genetic information over time. cross reacts with mouse, rat and dog.
- Purification
- Purified
- Immunogène
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Synthetic human MSH6 peptide.
Type of Immunogen: Synthetic peptide - Clone
- 44
- Isotype
- IgG1
- Top Product
- Discover our top product MSH6 Anticorps primaire
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- Indications d'application
- Approved: IP, WB (1:100 - 1:500)
- Commentaires
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Buffer contains: 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Store at 2-8°C. Do not freeze.
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- Antigène
- MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
- Autre désignation
- MSH6 (MSH6 Produits)
- Synonymes
- anticorps GTBP, anticorps GTMBP, anticorps HNPCC5, anticorps HSAP, anticorps p160, anticorps cb326, anticorps wu:fb36c12, anticorps LOC100227810, anticorps AU044881, anticorps AW550279, anticorps Gtmbp, anticorps mutS homolog 6, anticorps mutS homolog 6 (E. coli), anticorps DNA mismatch repair protein, anticorps MSH6, anticorps msh6, anticorps Msh6
- Sujet
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Name/Gene ID: MSH6
Synonyms: MSH6, GTBP, HSAP, GTMBP, MutS (E. coli) homolog 6, HMSH6, Sperm-associated protein, p160, G/T mismatch-binding protein, HNPCC5, MutS homolog 6 (E. coli), MutS-alpha 160 kDa subunit - ID gène
- 2956
- Pathways
- Réparation de l'ADN, Chromatin Binding, Production of Molecular Mediator of Immune Response
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