S100A8 anticorps (Biotin)

N° du produit ABIN379949

L’anticorps anti-S100A8 Monoclonal produit chez le Souris a été validé pour IHC, ELISA et IHC (p). Il convient pour la détection de S100A8 dans des échantillons provenant de Humain. }

Aperçu rapide pour S100A8 anticorps (Biotin) (ABIN379949)

Antigène: S100A8 (S100 Calcium Binding Protein A8 (S100A8))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp S100A8 est conjugé à/à la Biotin

Application: Immunohistochemistry (IHC), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 8-5C2

Détail du produit anti-S100A8 anticorps (Biotin)

Specificité: The antigen is MRP8, the epitope is suspected in the central portion of the peptide. Antigen distribution: Isolated cells: The antigen is found in granulocytes and monocytes but not in other blood cells. In cultured monocytes, maximum MRP8 expression is found after 3 - 4 days. Myeloid leukaemia stains positively. Tissue sections: MRP8 is found in a distinct subpopulation of inflammatory perivascular infiltrates of the myelo-monocytic lineage. Macrophages synthesise MRP8 increasingly during the late stages of inflammation. A low MRP8 (and high MRP- 14) expression by macrophages was also reported in granulomatous diseases such as tuberculosis and sarcoidis. In non-granulomatous chronic inflammatory diseases such as chronic rheumatoid arthritis or chronic rejection after allograft transplantation, MRP8 and MRP14 positive cells consist of different subpopulations. Specificity: Human: MRP8 in stimulated monocytes and macrophages in late phase or chronic inflammation. Other: The antibody reacts with bovine spleen but does not react with rat tissues. It shows a diffuse reaction with swine spleen.

Purification: Affinity purified

Immunogène: Cultured human monocytes

Information d'application

Indications d'application: Approved: ELISA, IHC, IHC-P

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: 0.5 mL distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS  pH 7.2, 10 mg/mL BSA, 0.01 % thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 4°C.

Détails sur S100A8

Antigène: S100A8 (S100 Calcium Binding Protein A8 (S100A8))

Autre désignation: S100A8 / MRP8

Sujet: Name/Gene ID: S100A8

Synonyms: S100A8, 60B8AG, CFAG, CAGA, Calgranulin A, Calgranulin-A, Calprotectin L1L subunit, Cystic fibrosis antigen, CGLA, L1Ag, NIF, p8, Protein S100-A8, MRP8, Urinary stone protein band A, CP-10, MA387, MRP-8

ID gène: 6279

UniProt: P05109

Pathways: Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, S100 Proteins