SENP2 anticorps (C-Term)

N° du produit ABIN388045

Détail du produit anti-SENP2 anticorps

Antigène: SENP2 (SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2))

Épitope: AA 502-533, C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SENP2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This SENP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 502-533 amino acids from the C-terminal region of human SENP2.

Clone: RB2705

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-SENP2 (ABIN388045)

Maruyama, Lin, Chiu, Yu, Porter, Hsu: "Extraembryonic but not embryonic SUMO-specific protease 2 is required for heart development." dans: Scientific reports, Vol. 6, pp. 20999, (2016) (PubMed).

La Salle, Sun, Zhang, Matunis, Handel: "Developmental control of sumoylation pathway proteins in mouse male germ cells." dans: Developmental biology, Vol. 321, Issue 1, pp. 227-37, (2008) (PubMed).

Détails sur SENP2

Antigène: SENP2 (SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2))

Autre désignation: SENP2 (SENP2 Produits)

Synonymes: anticorps 2310007L05Rik, anticorps 4930538C18Rik, anticorps AI646780, anticorps AW554757, anticorps Smt3ip2, anticorps SuPr-1, anticorps mKIAA1331, anticorps AXAM2, anticorps SMT3IP2, anticorps Axam, anticorps SUMO/sentrin specific peptidase 2, anticorps SUMO1/sentrin/SMT3 specific peptidase 2, anticorps Sumo1/sentrin/SMT3 specific peptidase 2, anticorps Senp2, anticorps SENP2

Sujet: SUMO is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1, SUMO2, and SUMO3 into the conjugatable mature forms and catalyze the deconjugation of these same SUMO proteins from their targeted substrates. SENP2 may also down-regulate CTNNB1 levels and thereby modulate the Wnt pathway.

Poids moléculaire: 67855

ID gène: 59343

NCBI Accession: NP_067640

UniProt: Q9HC62

Pathways: Chromatin Binding