SENP2 anticorps (C-Term)

N° du produit ABIN6264984

L’anticorps anti-SENP2 Polyclonal Lapin est utilisé pour la détection de SENP2 dans des échantillons de Humain, Souris, Rat et Singe. Il a été validé pour WB, IHC, IF et ICC.

Aperçu rapide pour SENP2 anticorps (C-Term) (ABIN6264984)

Antigène: SENP2 (SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2))

Reactivité: Humain, Souris, Rat, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SENP2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-SENP2 anticorps

Épitope: C-Term

Fonction: SENP2 Antibody

Specificité: SENP2 Antibody detects endogenous levels of total SENP2

Homologie: Pig,Bovine,Horse,Sheep,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human SENP2, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IF/ICC 1:200-1:500, IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur SENP2

Antigène: SENP2 (SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2))

Autre désignation: SENP2

Sujet:

Description: Protease that catalyzes two essential functions in the SUMO pathway. The first is the hydrolysis of an alpha-linked peptide bond at the C-terminal end of the small ubiquitin-like modifier (SUMO) propeptides, SUMO1, SUMO2 and SUMO3 leading to the mature form of the proteins. The second is the deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins, by cleaving an epsilon-linked peptide bond between the C-terminal glycine of the mature SUMO and the lysine epsilon-amino group of the target protein. May down-regulate CTNNB1 levels and thereby modulate the Wnt pathway. Deconjugates SUMO2 from MTA1. Plays a dynamic role in adipogenesis by desumoylating and promoting the stabilization of CEBPB (PubMed:20194620).

Gene: SENP2

Poids moléculaire: 68 kDa

ID gène: 59343

UniProt: Q9HC62

Pathways: Chromatin Binding