Caspase 10 anticorps (AA 164-192)

N° du produit ABIN388121

L’anticorps anti-Caspase 10 Polyclonal Lapin est utilisé pour la détection de Caspase 10 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour Caspase 10 anticorps (AA 164-192) (ABIN388121)

Antigène: Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Caspase 10 est non-conjugé

Application: Western Blotting (WB)

Clone: RB18398

Détail du produit anti-Caspase 10 anticorps

Épitope: AA 164-192

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This CASP10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 164-192 amino acids from the Central region of human CASP10.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur Caspase 10

Antigène: Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))

Autre désignation: CASP10

Sujet: CASP10 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in the protein are associated with apoptosis defects seen in type II autoimmune lymphoproliferative syndrome.

Poids moléculaire: 58951

ID gène: 843

NCBI Accession: NP_001193453, NP_001193471, NP_001221, NP_116756, NP_116758, NP_116759

UniProt: Q92851

Pathways: Apoptose, Caspase Cascade in Apoptosis