ATG4B anticorps (AA 258-284)

N° du produit ABIN388497

Cet anticorps anti-ATG4B est un anticorps Lapin Polyclonal détectant ATG4B dans WB et IHC (p). Adapté pour Humain.

Aperçu rapide pour ATG4B anticorps (AA 258-284) (ABIN388497)

Antigène: ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATG4B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB11843

Détail du produit anti-ATG4B anticorps

Épitope: AA 258-284

Homologie: B, C, Zf, M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This ATG4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 258-284 amino acids from human ATG4B.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur ATG4B

Antigène: ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

Autre désignation: ATG4B

Sujet: Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG4, a cysteine protease required for autophagy, cleaves the C-terminal part of MAP1LC3 to form the activated molecule LC3-I. LC3-I is subsequently conjugated with phosphatidylethanolamine at the C-terminal glycine to form LC3-II, a marker for autophagy via its capacity to bind to autophagosomes.

Poids moléculaire: 44294

ID gène: 23192

NCBI Accession: NP_037457, NP_847896

UniProt: Q9Y4P1

Pathways: Autophagy