LAMP1 anticorps (N-Term)

N° du produit ABIN388566

Cité dans 4 publications. Cet anticorps anti-LAMP1 Polyclonal Lapin (Clone RB12577) (ABIN388566) détecte spécifiquement LAMP1 dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour LAMP1 anticorps (N-Term) (ABIN388566)

Antigène: LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LAMP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB12577

Détail du produit anti-LAMP1 anticorps

Épitope: AA 125-154, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This LAMP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 125-154 amino acids from the N-terminal region of human LAMP1.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-LAMP1 (ABIN388566)

Funk, Mrak, Kuret: "Granulovacuolar degeneration (GVD) bodies of Alzheimer's disease (AD) resemble late-stage autophagic organelles." dans: Neuropathology and applied neurobiology, Vol. 37, Issue 3, pp. 295-306, (2011) (PubMed).

Kim, Woo, Yoon, Lee, An, Choi, Hwang, Yoon, Lee: "Involvement of autophagy in oncogenic K-Ras-induced malignant cell transformation." dans: The Journal of biological chemistry, Vol. 286, Issue 15, pp. 12924-32, (2011) (PubMed).

Hnasko, Lin, McGarvey, Stanker: "A rapid method to improve protein detection by indirect ELISA." dans: Biochemical and biophysical research communications, Vol. 410, Issue 4, pp. 726-31, (2011) (PubMed).

Byun, Yoon, An, Park, Kang, Kim, Lee: "The Rac1/MKK7/JNK pathway signals upregulation of Atg5 and subsequent autophagic cell death in response to oncogenic Ras." dans: Carcinogenesis, Vol. 30, Issue 11, pp. 1880-8, (2009) (PubMed).

Détails sur LAMP1

Antigène: LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

Autre désignation: LAMP1

Sujet: LAMP1 is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis.

Poids moléculaire: 44882

ID gène: 3916

NCBI Accession: NP_005552

UniProt: P11279

Pathways: Autophagy