UVRAG anticorps (AA 366-398)

N° du produit ABIN388587

Cet anticorps anti-UVRAG Polyclonal Lapin (Clone RB10847) (ABIN388587) détecte spécifiquement UVRAG dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour UVRAG anticorps (AA 366-398) (ABIN388587)

Antigène: UVRAG (UV Radiation Resistance Associated Gene (UVRAG))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UVRAG est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB10847

Détail du produit anti-UVRAG anticorps

Épitope: AA 366-398

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This UVRAG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 366-398 amino acids from the Central region of human UVRAG.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur UVRAG

Antigène: UVRAG (UV Radiation Resistance Associated Gene (UVRAG))

Autre désignation: UVRAG

Sujet: UVRAG complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer.

Poids moléculaire: 78151

ID gène: 7405

NCBI Accession: NP_003360

UniProt: Q9P2Y5