URI1 anticorps (C-Term)

N° du produit ABIN388684

Cet anticorps Lapin Polyclonal détecte spécifiquement URI1 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour URI1 anticorps (C-Term) (ABIN388684)

Antigène: URI1 (URI1, Prefoldin-Like Chaperone (URI1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp URI1 est non-conjugé

Application: Western Blotting (WB)

Clone: RB9809

Détail du produit anti-URI1 anticorps

Épitope: AA 347-376, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This RMP (URI) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 347-376 amino acids from the C-terminal region of human RMP (URI).

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur URI1

Antigène: URI1 (URI1, Prefoldin-Like Chaperone (URI1))

Autre désignation: RMP (URI)

Sujet: The protein encoded by this gene binds to RNA polymerase II subunit 5 (RPB5) and negatively modulates transcription through its binding to RPB5. The encoded protein seems to have inhibitory effects on various types of activated transcription, but it requires the RPB5-binding region. This protein acts as a corepressor. It is suggested that it may require signaling processes for its function or that it negatively modulates genes in the chromatin structure. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Poids moléculaire: 59832

ID gène: 8725

NCBI Accession: NP_001239570, NP_003787

UniProt: O94763