GDF2 anticorps (N-Term)

N° du produit ABIN388817

2+ publications sont disponibles pour ce produit. L’anticorps anti-GDF2 Polyclonal produit chez le Lapin a été validé pour WB et IHC (p). Il convient pour la détection de GDF2 dans des échantillons provenant de Humain et Souris. }

Aperçu rapide pour GDF2 anticorps (N-Term) (ABIN388817)

Antigène: GDF2 (Growth Differentiation Factor 2 (GDF2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GDF2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB2206

Détail du produit anti-GDF2 anticorps

Épitope: AA 8-37, N-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This BMP9 (GDF2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-37 amino acids from the N-terminal region of human BMP9 (GDF2).

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-GDF2 (ABIN388817)

Herrera, García-Álvaro, Cruz, Walsh, Fernández, Roncero, Fabregat, Sánchez, Inman: "BMP9 Is a Proliferative and Survival Factor for Human Hepatocellular Carcinoma Cells." dans: PLoS ONE, Vol. 8, Issue 7, pp. e69535, (2013) (PubMed).

Herrera, van Dinther, Ten Dijke, Inman: "Autocrine bone morphogenetic protein-9 signals through activin receptor-like kinase-2/Smad1/Smad4 to promote ovarian cancer cell proliferation." dans: Cancer research, Vol. 69, Issue 24, pp. 9254-62, (2009) (PubMed).

Détails sur GDF2

Antigène: GDF2 (Growth Differentiation Factor 2 (GDF2))

Autre désignation: BMP9 (GDF2)

Sujet: GDF2 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in rodents suggest that this protein plays a role in the adult liver and in differentiation of cholinergic central nervous system neurons.

Poids moléculaire: 47320

ID gène: 2658

NCBI Accession: NP_057288

UniProt: Q9UK05

Pathways: Transition Metal Ion Homeostasis