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GDF5 anticorps (N-Term)

GDF5 Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal RB01877 unconjugated
N° du produit ABIN388820
  • Antigène Voir toutes GDF5 Anticorps
    GDF5 (Growth Differentiation Factor 5 (GDF5))
    Épitope
    • 10
    • 9
    • 8
    • 8
    • 7
    • 7
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 13-41, N-Term
    Reactivité
    • 73
    • 33
    • 19
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 77
    • 3
    • 3
    • 3
    • 1
    Lapin
    Clonalité
    • 81
    • 6
    Polyclonal
    Conjugué
    • 35
    • 14
    • 10
    • 6
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GDF5 est non-conjugé
    Application
    • 73
    • 45
    • 45
    • 8
    • 8
    • 7
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogène
    This GDF5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-41 amino acids from the N-terminal region of human GDF5.
    Clone
    RB01877
    Isotype
    Ig Fraction
    Top Product
    Discover our top product GDF5 Anticorps primaire
  • Indications d'application
    WB: 1:1000. IHC-P: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Liu, Lin, Sytwu, Chang: "GDF-5 is suppressed by IL-1beta and enhances TGF-beta3-mediated chondrogenic differentiation in human rheumatoid fibroblast-like synoviocytes." dans: Experimental and molecular pathology, Vol. 88, Issue 1, pp. 163-70, (2010) (PubMed).

  • Antigène
    GDF5 (Growth Differentiation Factor 5 (GDF5))
    Autre désignation
    GDF5 (GDF5 Produits)
    Synonymes
    anticorps CDMP1, anticorps gdf, anticorps gdf-5, anticorps GDF5, anticorps BDA1C, anticorps BMP14, anticorps LAP4, anticorps OS5, anticorps SYM1B, anticorps SYNS2, anticorps Cdmp-1, anticorps bp, anticorps brp, anticorps Cdmp1, anticorps growth differentiation factor 5 L homeolog, anticorps growth differentiation factor 5, anticorps gdf5.L, anticorps GDF5, anticorps Gdf5
    Sujet
    GDF5 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Mutations in this gene are associated with acromesomelic dysplasia, Hunter-Thompson type, brachydactyly, type C, and chondrodysplasia, Grebe type. These associations confirm that the gene product plays a role in skeletal development.
    Poids moléculaire
    55411
    ID gène
    8200
    NCBI Accession
    NP_000548
    UniProt
    P43026
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