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GDF5 anticorps

GDF5 Reactivité: Humain, Souris, Rat WB, IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7074131
  • Antigène Voir toutes GDF5 Anticorps
    GDF5 (Growth Differentiation Factor 5 (GDF5))
    Reactivité
    • 73
    • 32
    • 18
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 77
    • 3
    • 3
    • 3
    • 1
    Lapin
    Clonalité
    • 81
    • 6
    Polyclonal
    Conjugué
    • 35
    • 14
    • 10
    • 6
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GDF5 est non-conjugé
    Application
    • 73
    • 45
    • 44
    • 9
    • 8
    • 6
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
     Réactivité croisée
    Humain, Rat
    Purification
    Affinity purification
    Immunogène
    KLH conjugated Synthetic peptide corresponding to Mouse GDF 5
    Top Product
    Discover our top product GDF5 Anticorps primaire
  • Indications d'application
    WB (H,M) 1:500-1:1000, IHC/IF (H,R) 1:200-1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
  • Antigène
    GDF5 (Growth Differentiation Factor 5 (GDF5))
    Autre désignation
    GDF 5 (GDF5 Produits)
    Synonymes
    anticorps CDMP1, anticorps gdf, anticorps gdf-5, anticorps GDF5, anticorps BDA1C, anticorps BMP14, anticorps LAP4, anticorps OS5, anticorps SYM1B, anticorps SYNS2, anticorps Cdmp-1, anticorps bp, anticorps brp, anticorps Cdmp1, anticorps growth differentiation factor 5 L homeolog, anticorps growth differentiation factor 5, anticorps gdf5.L, anticorps GDF5, anticorps Gdf5
    Sujet
    Growth factor involved in bone and cartilage formation. During cartilage development regulates differentiation of chondrogenic tissue through two pathways. Firstly, positively regulates differentiation of chondrogenic tissue through its binding of high affinity with BMPR1B and of less affinity with BMPR1A, leading to induction of SMAD1-SMAD5-SMAD8 complex phosphorylation and then SMAD protein signaling transduction . Secondly, negatively regulates chondrogenic differentiation through its interaction with NOG . Required to prevent excessive muscle loss upon denervation. This function requires SMAD4 and is mediated by phosphorylated SMAD1/5/8 .
    Poids moléculaire
    55 kDa
    ID gène
    14563
    NCBI Accession
    NP_032135
    UniProt
    P43027
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