UBE2L6 anticorps (C-Term)

N° du produit ABIN388854

Cité dans 3 publications. Cet anticorps anti-UBE2L6 Polyclonal Lapin (Clone RB4157) (ABIN388854) détecte spécifiquement UBE2L6 dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour UBE2L6 anticorps (C-Term) (ABIN388854)

Antigène: UBE2L6 (Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBE2L6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB4157

Détail du produit anti-UBE2L6 anticorps

Épitope: AA 123-153, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This UBE2L6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 123-153 amino acids from the C-terminal region of human UBE2L6.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-UBE2L6 (ABIN388854)

Zhao, Sridharan, Chen, Baker, Wang, Krug: "Influenza B virus non-structural protein 1 counteracts ISG15 antiviral activity by sequestering ISGylated viral proteins." dans: Nature communications, Vol. 7, pp. 12754, (2018) (PubMed).

Pietschmann, Buchwald, Müller, Knauer, Kögl, Heinzel, Krämer: "Differential regulation of PML-RAR? stability by the ubiquitin ligases SIAH1/SIAH2 and TRIAD1." dans: The international journal of biochemistry & cell biology, Vol. 44, Issue 1, pp. 132-8, (2011) (PubMed).

Krämer, Müller, Buchwald, Reichardt, Heinzel: "Mechanism for ubiquitylation of the leukemia fusion proteins AML1-ETO and PML-RARalpha." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 22, Issue 5, pp. 1369-79, (2008) (PubMed).

Détails sur UBE2L6

Antigène: UBE2L6 (Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6))

Autre désignation: UBE2L6

Sujet: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2L6 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to function in the E6/E6-ap-induced ubiquitination of p53.

Poids moléculaire: 17769

ID gène: 9246

NCBI Accession: NP_004214, NP_937826

UniProt: O14933