ZMPSTE24 anticorps (AA 400-430)

N° du produit ABIN389048

L’anticorps Lapin Polyclonal anti-ZMPSTE24 a été validé pour WB et IHC (p). Il convient pour détecter ZMPSTE24 dans des échantillons de Humain. Il y a 3+ publications disponibles.

Aperçu rapide pour ZMPSTE24 anticorps (AA 400-430) (ABIN389048)

Antigène: ZMPSTE24 (Zmpste24) (Zinc Metalloproteinase, Ste24 (Zmpste24))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZMPSTE24 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB04772

Détail du produit anti-ZMPSTE24 anticorps

Épitope: AA 400-430

Homologie: M

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This ZMPSTE24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 400-430 amino acids from the Central region of human ZMPSTE24.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-ZMPSTE24 (ABIN389048)

Akinci, Sankella, Gilpin, Ozono, Garg, Agarwal: "Progeroid syndrome patients with ZMPSTE24 deficiency could benefit when treated with rapamycin and dimethylsulfoxide." dans: Cold Spring Harbor molecular case studies, Vol. 3, Issue 1, pp. a001339, (2017) (PubMed).

Liu, Wang, Chan, Tjia, Deng, Guan, Huang, Li, Chau, Chen, Pei, Pendas, Cadiñanos, López-Otín, Tse, Hutchison, Chen, Cao, Cheah, Tryggvason, Zhou: "Genomic instability in laminopathy-based premature aging." dans: Nature medicine, Vol. 11, Issue 7, pp. 780-5, (2005) (PubMed).

Corrigan, Kuszczak, Rusinol, Thewke, Hrycyna, Michaelis, Sinensky: "Prelamin A endoproteolytic processing in vitro by recombinant Zmpste24." dans: The Biochemical journal, Vol. 387, Issue Pt 1, pp. 129-38, (2005) (PubMed).

Détails sur ZMPSTE24

Antigène: ZMPSTE24 (Zmpste24) (Zinc Metalloproteinase, Ste24 (Zmpste24))

Autre désignation: ZMPSTE24

Sujet: ZMPSTE24 is a zinc metalloprotease similar to yeast Ste24p. It is an integral membrane protein belonging to peptidase family M48 and is found in the endoplasmic reticulum and possibly in the Golgi compartment. It is thought to be involved in the proteolytic processing of farnesylated proteins.

Poids moléculaire: 54813

ID gène: 10269

NCBI Accession: NP_005848

UniProt: O75844