FNTA anticorps (AA 88-118)

N° du produit ABIN389057

L’anticorps Lapin Polyclonal anti-FNTA a été validé pour WB. Il convient pour détecter FNTA dans des échantillons de Humain et Souris.

Aperçu rapide pour FNTA anticorps (AA 88-118) (ABIN389057)

Antigène: FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FNTA est non-conjugé

Application: Western Blotting (WB)

Clone: RB4792

Détail du produit anti-FNTA anticorps

Épitope: AA 88-118

Homologie: B, Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This FNTA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-118 amino acids from the Central region of human FNTA.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur FNTA

Antigène: FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))

Autre désignation: FNTA

Sujet: FNTA, also known as CAAX farnesyltransferase (FTase), attaches a farnesyl group from farnesyl pyrophosphate to cysteine residues at the fourth position from the C terminus of proteins that end in the so-called CAAX box, where C is cysteine, A is usually but not always an aliphatic amino acid, and X is typically methionine or serine. This type of posttranslational modification provides a mechanism for membrane localization of proteins that lack a transmembrane domain. This enzyme has the remarkable property of farnesylating peptides as short as four residues in length that conform to the CAAX consensus sequence. FNTA is also a specific cytoplasmic interactor of the transforming growth factor-beta and activin type I receptors. It is likely to be a key component of the signaling pathway which involves p21ras, an important substrate for farnesyltransferase.

Poids moléculaire: 44409

ID gène: 2339

NCBI Accession: NP_002018

UniProt: P49354

Pathways: Response to Water Deprivation, Regulation of G-Protein Coupled Receptor Protein Signaling