CDK2 anticorps (pThr160)

N° du produit ABIN389540

Il existe 1 publication pour ce produit. L’anticorps anti-CDK2 Polyclonal Lapin est utilisé pour la détection de CDK2 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour CDK2 anticorps (pThr160) (ABIN389540)

Antigène: CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDK2 est non-conjugé

Application: Western Blotting (WB)

Clone: RB7342

Détail du produit anti-CDK2 anticorps

Épitope: pThr160

Homologie: B, Ha, M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This Cdk2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T160 of human Cdk2.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-CDK2 (ABIN389540)

Wang, Liu, Zhao, Song, Wang, Wang, Sun: "Phosphorylation of CDK2 on threonine 160 influences silencing of sex chromosome during male meiosis." dans: Biology of reproduction, Vol. 90, Issue 6, pp. 138, (2014) (PubMed).

Détails sur CDK2

Antigène: CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

Autre désignation: Cdk2

Sujet: Cdk2 is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.

Poids moléculaire: 33930

ID gène: 1017

NCBI Accession: NP_001789, NP_439892

UniProt: P24941

Pathways: Signalisation PI3K-Akt, Cycle Cellulaire, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA