MYT1 anticorps (pThr495)

N° du produit ABIN389599

Détail du produit anti-MYT1 anticorps

Antigène: MYT1 (Myelin Transcription Factor 1 (MYT1))

Épitope: pThr495

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MYT1 est non-conjugé

Application: Western Blotting (WB), Dot Blot (DB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This MYT1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T495 of human MYT1.

Clone: RB7898

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100. DB: 1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-MYT1 (ABIN389599)

Mac?rek, Lindqvist, Lim, Lampson, Klompmaker, Freire, Clouin, Taylor, Yaffe, Medema: "Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery." dans: Nature, Vol. 455, Issue 7209, pp. 119-23, (2008) (PubMed).

Détails sur MYT1

Antigène: MYT1 (Myelin Transcription Factor 1 (MYT1))

Autre désignation: MYT1 (MYT1 Produits)

Synonymes: anticorps fc56h05, anticorps myt1, anticorps si:dkey-202m22.5, anticorps wu:fc56h05, anticorps C20orf36, anticorps MTF1, anticorps MYTI, anticorps PLPB1, anticorps ZC2HC4A, anticorps Nzf2, anticorps Nzf2a, anticorps Nzf2b, anticorps Nztf2, anticorps myelin transcription factor 1, anticorps myelin transcription factor 1a, anticorps myelin transcription factor 1 S homeolog, anticorps MYT1, anticorps myt1a, anticorps Myt1, anticorps myt1.S

Sujet: The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase preferentially phosphorylates and inactivates cell division cycle 2 protein (CDC2), and thus negatively regulates cell cycle G2/M transition. This kinase is associated with the membrane throughout the cell cycle. Its activity is highly regulated during the cell cycle. Protein kinases AKT1/PKB and PLK (Polo-like kinase) have been shown to phosphorylate and regulate the activity of this kinase. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Poids moléculaire: 54521

ID gène: 9088

NCBI Accession: NP_001245379, NP_001245380, NP_004194, NP_872629

UniProt: Q99640

Pathways: Cycle Cellulaire