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SMAD4 anticorps (pThr277)

Name: SMAD4 anticorps (pThr277)
SKU: ABIN389658
Price: 475.5 EUR
Availability: InStock

SMAD4 Reactivité: Humain, Souris WB Hôte: Lapin Polyclonal RB07971 unconjugated

Western blot analysis of lysates from NIH/3T3 cell line, untreated or treated with TGF-β(100 ng/mL, 30 min), using Phospho-SD4 Antibody (upper) or Beta-actin (lower). (SMAD4 anticorps (pThr277))

1 image

(1 reference)

N° du produit ABIN389658

Fiche de données

Antigène Voir toutes SMAD4 Anticorps

SMAD4 (SMAD Family Member 4 (SMAD4))
Épitope
11

9

9

8

7

7

7

5

4

4

4

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1
pThr277
Reactivité
98

41

37

4

3

3

2

2

2

2

2

2

1

1
Humain, Souris
Hôte
87

11

1
Lapin
Anticorps secondaires appropriés
Clonalité
75

24
Polyclonal
Conjugué
55

9

8

4

3

2

2

2

2

2

2

2

1

1

1

1

1

1
Cet anticorp SMAD4 est non-conjugé
Application
64

46

36

29

22

11

9

7

6

3

2

2

2

1

1

1

1

1
Western Blotting (WB)

Homologie

Rat

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène

This SMAD4 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T277 of human SMAD4.

Clone

RB07971

Isotype

Ig Fraction

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SMAD4 Reactivité: Humain WB, ELISA, IHC, ICC, FACS Hôte: Souris Monoclonal 4G1C6 unconjugated

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SMAD4 Reactivité: Humain WB, ELISA, IHC, IF, FACS Hôte: Lapin Polyclonal unconjugated

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SMAD4 Reactivité: Humain, Souris, Rat, Singe WB, ELISA, IF, IHC (p) Hôte: Lapin Polyclonal unconjugated

anti-SMAD Family Member 4 (SMAD4) (AA 27-195) antibody
SMAD4 Reactivité: Humain WB, ELISA, IHC, IP Hôte: Lapin Polyclonal unconjugated

anti-SMAD Family Member 4 (SMAD4) (AA 400-428), (C-Term) antibody
SMAD4 Reactivité: Humain WB, IF, IHC (p), FACS Hôte: Lapin Polyclonal RB20720 unconjugated

anti-SMAD Family Member 4 (SMAD4) (AA 118-240) antibody
SMAD4 Reactivité: Humain WB, IF, IHC (p) Hôte: Lapin Polyclonal unconjugated

Indications d'application

WB: 1:500

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

4 °C,-20 °C

Stockage commentaire

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption

6 months
Arjunan, Gnanaprakasam, Ananth, Romej, Rajalakshmi, Prasad, Martin, Gurusamy, Thangaraju, Bhutia, Ganapathy: "Increased Retinal Expression of the Pro-Angiogenic Receptor GPR91 via BMP6 in a Mouse Model of Juvenile Hemochromatosis." dans: Investigative ophthalmology & visual science, Vol. 57, Issue 4, pp. 1612-9, (2016) (PubMed).
Antigène

SMAD4 (SMAD Family Member 4 (SMAD4))

Autre désignation

SMAD4 (SMAD4 Produits)

Synonymes

anticorps smad4, anticorps DPC4, anticorps JIP, anticorps MADH4, anticorps MYHRS, anticorps AW743858, anticorps D18Wsu70e, anticorps Madh4, anticorps XSmad4alpha, anticorps Xsmad4, anticorps dpc4, anticorps jip, anticorps madh4, anticorps xsmad4a, anticorps SMAD family member 4, anticorps Smad4 protein, anticorps SMAD family member 4, gene 1 L homeolog, anticorps SMAD4, anticorps smad4, anticorps Smad4, anticorps smad4.1.L

Sujet

Common mediator of signal transduction by TGF-beta (transforming growth factor) superfamily, SMAD4 is the common SMAD (co-SMAD). It promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. It may act as a tumor suppressor.

Poids moléculaire

60439

ID gène

4089

NCBI Accession

NP_005350

UniProt

Q13485

Pathways

Cycle Cellulaire, Chromatin Binding, Autophagy