WEE1 anticorps (pSer123)

N° du produit ABIN389681

L’anticorps Lapin Polyclonal anti-WEE1 a été validé pour IHC (p) et DB. Il convient pour détecter WEE1 dans des échantillons de Humain. Il y a 1 publication disponible.

Aperçu rapide pour WEE1 anticorps (pSer123) (ABIN389681)

Antigène: WEE1 (WEE1 Homolog (S. Pombe) (WEE1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WEE1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Dot Blot (DB)

Clone: RB07865

Détail du produit anti-WEE1 anticorps

Épitope: pSer123

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This Wee1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S123 of human Wee1.

Isotype: Ig Fraction

Information d'application

Indications d'application: IHC-P: 1:50~100. DB: 1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-WEE1 (ABIN389681)

Müller, Lutter, Püschel: "Persistence of the cell-cycle checkpoint kinase Wee1 in SadA- and SadB-deficient neurons disrupts neuronal polarity." dans: Journal of cell science, Vol. 123, Issue Pt 2, pp. 286-94, (2010) (PubMed).

Détails sur WEE1

Antigène: WEE1 (WEE1 Homolog (S. Pombe) (WEE1))

Autre désignation: Wee1

Sujet: This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.

Poids moléculaire: 71597

ID gène: 7465

NCBI Accession: NP_001137448, NP_003381

UniProt: P30291

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases, M Phase