TERT anticorps (pTyr707)

N° du produit ABIN390002

L’anticorps Lapin Polyclonal anti-TERT a été validé pour IF et DB. Il convient pour détecter TERT dans des échantillons de Humain. Il y a 2+ publications disponibles.

Aperçu rapide pour TERT anticorps (pTyr707) (ABIN390002)

Antigène: TERT (Telomerase Reverse Transcriptase (TERT))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TERT est non-conjugé

Application: Immunofluorescence (IF), Dot Blot (DB)

Clone: RB16840

Détail du produit anti-TERT anticorps

Épitope: pTyr707

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This TERT Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y707 of human TERT.

Isotype: Ig Fraction

Information d'application

Indications d'application: IF: 1:10~50. DB: 1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-TERT (ABIN390002)

Radan, Hughes, Teichroeb, Vieira Zamora, Jewer, Postovit, Betts: "Microenvironmental regulation of telomerase isoforms in human embryonic stem cells." dans: Stem cells and development, Vol. 23, Issue 17, pp. 2046-66, (2014) (PubMed).

Pecec, Voiculetz: "An antibody sandwich method for the radioimmunoassay of human alpha-fetoprotein." dans: Immunochemistry, Vol. 11, Issue 12, pp. 771-5, (1975) (PubMed).

Détails sur TERT

Antigène: TERT (Telomerase Reverse Transcriptase (TERT))

Autre désignation: TERT

Sujet: Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks.

Poids moléculaire: 126997

ID gène: 7015

NCBI Accession: NP_001180305, NP_937983

UniProt: O14746

Pathways: Telomere Maintenance