BACE2 anticorps (AA 336-365)

N° du produit ABIN390067

Détail du produit anti-BACE2 anticorps

Antigène: BACE2 (beta-Site APP-Cleaving Enzyme 2 (BACE2))

Épitope: AA 336-365

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BACE2 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This BACE2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-365 amino acids from the Central region of human BACE2.

Clone: RB2187

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur BACE2

Antigène: BACE2 (beta-Site APP-Cleaving Enzyme 2 (BACE2))

Autre désignation: BACE2 (BACE2 Produits)

Synonymes: anticorps AEPLC, anticorps ALP56, anticorps ASP1, anticorps ASP21, anticorps BAE2, anticorps CEAP1, anticorps DRAP, anticorps 1110059C24Rik, anticorps AI850424, anticorps ARP1, anticorps CDA13, anticorps beta-site APP-cleaving enzyme 2, anticorps BACE2, anticorps Bace2

Sujet: Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases, one of which is the protein encoded by BACE2. This gene localizes to the 'Down critical region' of chromosome 21. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease.

Poids moléculaire: 56180

ID gène: 25825

NCBI Accession: NP_036237, NP_620476, NP_620477

UniProt: Q9Y5Z0