XIAP anticorps (N-Term)

N° du produit ABIN390070

Cet anticorps Lapin Polyclonal détecte spécifiquement XIAP dans WB et IHC (p). Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour XIAP anticorps (N-Term) (ABIN390070)

Antigène: XIAP (X-Linked Inhibitor of Apoptosis (XIAP))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp XIAP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB01793

Détail du produit anti-XIAP anticorps

Épitope: AA 1-30, N-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This XIAP (BIRC4) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human XIAP (BIRC4).

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur XIAP

Antigène: XIAP (X-Linked Inhibitor of Apoptosis (XIAP))

Autre désignation: XIAP (BIRC4)

Sujet: BIRC4 is a member of a family of proteins which inhibit apoptosis through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2. Similar to API1, BIRC4 inhibits apoptosis induced by menadione, a potent inducer of free radicals, and ICE. BIRC4 also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7.

Poids moléculaire: 56685

ID gène: 331

NCBI Accession: NP_001158, NP_001191330

UniProt: P98170

Pathways: Apoptose, Caspase Cascade in Apoptosis, Transition Metal Ion Homeostasis