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Leptin Receptor anticorps (N-Term)

LEPR Reactivité: Humain WB, FACS, IHC (p) Hôte: Lapin Polyclonal RB02053 unconjugated
N° du produit ABIN390093
  • Antigène Voir toutes Leptin Receptor (LEPR) Anticorps
    Leptin Receptor (LEPR)
    Épitope
    • 16
    • 16
    • 10
    • 9
    • 7
    • 7
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 23-52, N-Term
    Reactivité
    • 113
    • 71
    • 50
    • 20
    • 12
    • 5
    • 4
    • 2
    Humain
    Hôte
    • 115
    • 15
    • 2
    • 2
    • 1
    • 1
    Lapin
    Clonalité
    • 113
    • 23
    Polyclonal
    Conjugué
    • 49
    • 11
    • 8
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Leptin Receptor est non-conjugé
    Application
    • 86
    • 47
    • 36
    • 35
    • 26
    • 25
    • 16
    • 11
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogène
    This Leptin Receptor (LEPR) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-52 amino acids from the N-terminal region of human Leptin Receptor (LEPR).
    Clone
    RB02053
    Isotype
    Ig Fraction
    Top Product
    Discover our top product LEPR Anticorps primaire
  • Indications d'application
    WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Antigène
    Leptin Receptor (LEPR)
    Abstract
    LEPR Produits
    Sujet
    Leptin, an adipocyte-specific hormone, regulates adipose-tissue mass through hypothalamic effects on satiety and energy expenditure by acting through the leptin receptor (LEPR). LEPR is a single-transmembrane-domain receptor of the cytokine receptor family that is identical to the mouse diabetes (db) gene product. During weight loss, leptin levels decrease, whereas soluble LEPR levels and the receptor bound fraction of leptin increases. The presence of LEPR in the absorptive cells of the small intestine suggests that leptin may have a physiological role in the regulation of nutrient absorption.
    Poids moléculaire
    132494
    ID gène
    3953
    NCBI Accession
    NP_001003679, NP_001003680, NP_001185616, NP_001185617, NP_001185618, NP_002294
    UniProt
    P48357
    Pathways
    Signalistation JAK/STAT, AMPK Signaling, Feeding Behaviour
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