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Glypican 3 anticorps (N-Term)

GPC3 Reactivité: Humain, Souris WB, IHC (p) Hôte: Lapin Polyclonal RB05031 unconjugated
N° du produit ABIN390317
  • Antigène Voir toutes Glypican 3 (GPC3) Anticorps
    Glypican 3 (GPC3)
    Épitope
    • 20
    • 16
    • 13
    • 11
    • 7
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-50, N-Term
    Reactivité
    • 152
    • 48
    • 47
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 96
    • 55
    • 2
    Lapin
    Clonalité
    • 81
    • 71
    • 1
    Polyclonal
    Conjugué
    • 63
    • 13
    • 8
    • 7
    • 7
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Glypican 3 est non-conjugé
    Application
    • 83
    • 82
    • 70
    • 51
    • 41
    • 26
    • 17
    • 17
    • 6
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogène
    This Glypican 3 (GPC3) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 amino acids from the N-terminal region of human Glypican 3 (GPC3).
    Clone
    RB05031
    Isotype
    Ig Fraction
    Top Product
    Discover our top product GPC3 Anticorps primaire
  • Indications d'application
    WB: 1:2000. WB: 1:2000. WB: 1:1000. IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Han, Ma, Zhao, Zhao, Batista, Zhou, Zhou, Yang, Wang, Bi, Xia, Bai, Garkavtsev, Zhang: "Identification of Glypican-3 as a potential metastasis suppressor gene in gastric cancer." dans: Oncotarget, Vol. 7, Issue 28, pp. 44406-44416, (2018) (PubMed).

  • Antigène
    Glypican 3 (GPC3)
    Abstract
    GPC3 Produits
    Synonymes
    anticorps GPC3, anticorps sgb, anticorps dgsx, anticorps sdys, anticorps sgbs, anticorps oci-5, anticorps sgbs1, anticorps DGSX, anticorps GTR2-2, anticorps MXR7, anticorps OCI-5, anticorps SDYS, anticorps SGB, anticorps SGBS, anticorps SGBS1, anticorps Glypican-3, anticorps glypican 3, anticorps gpc3, anticorps GPC3, anticorps Gpc3
    Sujet
    GPC3 is a cell surface proteoglycan that bears heparan sulfate. This protein may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. Members of the glypican-related integral membrane proteoglycan family contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol (GPI) linkage. These proteins may play a role in the control of cell division, growth regulation, and tumor predisposition. Deletion mutations in GPC3 are the cause of Simpson-Golabi-Behmel syndrome (SGBS), also known as Simpson dysmorphia syndrome (SDYS). SGBS is a condition characterized by pre- and postnatal overgrowth (gigantism) with visceral and skeletal anomalies.
    Poids moléculaire
    65563
    ID gène
    2719
    NCBI Accession
    NP_001158089, NP_001158091, NP_004475
    UniProt
    P51654
    Pathways
    Glycosaminoglycan Metabolic Process
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