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SNCAIP anticorps (C-Term)

SNCAIP Reactivité: Humain WB Hôte: Lapin Polyclonal RB7392 unconjugated
N° du produit ABIN390382
  • Antigène Voir toutes SNCAIP Anticorps
    SNCAIP (Synuclein, alpha Interacting Protein (SNCAIP))
    Épitope
    • 15
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 593-622, C-Term
    Reactivité
    • 26
    • 23
    • 17
    Humain
    Hôte
    • 37
    • 2
    Lapin
    Clonalité
    • 38
    • 1
    Polyclonal
    Conjugué
    • 15
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SNCAIP est non-conjugé
    Application
    • 27
    • 13
    • 13
    • 12
    • 7
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogène
    This Synphilin-1 (SNCAIP) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 593-622 amino acids from the C-terminal region of human Synphilin-1 (SNCAIP).
    Clone
    RB7392
    Isotype
    Ig Fraction
    Top Product
    Discover our top product SNCAIP Anticorps primaire
  • Indications d'application
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Antigène
    SNCAIP (Synuclein, alpha Interacting Protein (SNCAIP))
    Autre désignation
    Synphilin-1 (SNCAIP) (SNCAIP Produits)
    Synonymes
    anticorps sncaip, anticorps MGC88953, anticorps SNCAIP, anticorps LOC100221074, anticorps SYPH1, anticorps Sph1, anticorps Syph1, anticorps 2810407O15Rik, anticorps 4933427B05Rik, anticorps BB104594, anticorps synuclein alpha interacting protein, anticorps synuclein, alpha interacting protein, anticorps synuclein, alpha interacting protein (synphilin), anticorps SNCAIP, anticorps sncaip, anticorps Sncaip
    Sujet
    Parkinson is the second most common neurodegenerative disease after Alzheimers. About 1 percent of people over the age of 65 and 3 percent of people over the age of 75 are affected by the disease. The mutation is the most common cause of Parkinson disease identified to date. Synuclein alpha interacting protein (Synphilin-1) contains several protein-protein interaction domains and interacts with alpha synuclein in neurons. Mutations of SNCAIP have been linked to Parkinson disease. The amino acid sequence of synphilin-1 shows extensive homology with its human counterpart, especially in regions containing ankyrin-like motifs and the coiled-coil domain. Expression of mouse synphilin-1 in tissues is similar to its human counterpart. Synphilin-1 has an important role in the formation of aggregates and cytotoxicity in Parkinson disease and that Dorfin may be involved in the pathogenic process by ubiquitylation of synphilin-1. Role of synphilin-1 in synaptic function and protein degradation and in the molecular mechanisms leading to neurodegeneration in Parkinson disease
    Poids moléculaire
    100409
    ID gène
    9627
    NCBI Accession
    NP_001229864, NP_005451
    UniProt
    Q9Y6H5
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