ALS2 anticorps (C-Term)

N° du produit ABIN390394

Cet anticorps Lapin Polyclonal détecte spécifiquement ALS2 dans WB et IHC (p). Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour ALS2 anticorps (C-Term) (ABIN390394)

Antigène: ALS2 (Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALS2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB18853

Détail du produit anti-ALS2 anticorps

Épitope: AA 1248-1277, C-Term

Homologie: Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This ALS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1248-1277 amino acids from the C-terminal region of human ALS2.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur ALS2

Antigène: ALS2 (Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2))

Autre désignation: ALS2

Sujet: ALS2 contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in its gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis.

Poids moléculaire: 183634

ID gène: 57679

NCBI Accession: NP_001129217, NP_065970

UniProt: Q96Q42

Pathways: Skeletal Muscle Fiber Development