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ALS2 anticorps

ALS2 Reactivité: Humain, Souris IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7010503
  • Antigène Voir toutes ALS2 Anticorps
    ALS2 (Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2))
    Reactivité
    • 37
    • 11
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 34
    • 4
    • 1
    Lapin
    Clonalité
    • 35
    • 3
    Polyclonal
    Conjugué
    • 25
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ALS2 est non-conjugé
    Application
    • 22
    • 14
    • 13
    • 13
    • 7
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    Immunofluorescence (IF)
    Attributs du produit
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein of human ALS2 (NP_065970.2).
    Isotype
    IgG
    Top Product
    Discover our top product ALS2 Anticorps primaire
  • Indications d'application
    IF 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    ALS2 (Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2))
    Autre désignation
    ALS2 (ALS2 Produits)
    Synonymes
    anticorps als2, anticorps si:dkey-33m14.1, anticorps ALS2CR6, anticorps ALSJ, anticorps IAHSP, anticorps PLSJ, anticorps 3222402C23Rik, anticorps 9430073A21Rik, anticorps Als2cr6, anticorps Alsin, anticorps mKIAA1563, anticorps amyotrophic lateral sclerosis 2a (juvenile), anticorps alsin, anticorps ALS2, alsin Rho guanine nucleotide exchange factor, anticorps amyotrophic lateral sclerosis 2 (juvenile), anticorps als2a, anticorps CpipJ_CPIJ008258, anticorps CpipJ_CPIJ008260, anticorps ALS2, anticorps Als2
    Sujet
    The protein encoded by this gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene.
    ID gène
    57679
    UniProt
    Q96Q42
    Pathways
    Skeletal Muscle Fiber Development
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