Lamin B2 anticorps (C-Term)

N° du produit ABIN390698

L’anticorps Lapin Polyclonal anti-Lamin B2 a été validé pour WB. Il convient pour détecter Lamin B2 dans des échantillons de Humain. Il y a 1 publication disponible.

Aperçu rapide pour Lamin B2 anticorps (C-Term) (ABIN390698)

Antigène: Lamin B2 (LMNB2)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Lamin B2 est non-conjugé

Application: Western Blotting (WB)

Clone: RB19541

Détail du produit anti-Lamin B2 anticorps

Épitope: AA 476-504, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This Lamin B2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 476-504 amino acids from the C-terminal region of human Lamin B2.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-Lamin B2 (ABIN390698)

Jevti?, Edens, Li, Nguyen, Chen, Levy: "Concentration-dependent Effects of Nuclear Lamins on Nuclear Size in Xenopus and Mammalian Cells." dans: The Journal of biological chemistry, Vol. 290, Issue 46, pp. 27557-71, (2015) (PubMed).

Détails sur Lamin B2

Antigène: Lamin B2 (LMNB2)

Autre désignation: Lamin B2

Sujet: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Lamin B2 is one of the two B type proteins, B2.

Poids moléculaire: 69948

ID gène: 84823

NCBI Accession: NP_116126

UniProt: Q03252

Pathways: Apoptose, Caspase Cascade in Apoptosis