HMGCS2 anticorps (C-Term)

N° du produit ABIN390764

L’anticorps Lapin Polyclonal anti-HMGCS2 a été validé pour WB, FACS et IHC (p). Il convient pour détecter HMGCS2 dans des échantillons de Humain. Il y a 1 publication disponible.

Aperçu rapide pour HMGCS2 anticorps (C-Term) (ABIN390764)

Antigène: HMGCS2 (3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HMGCS2 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB19373

Détail du produit anti-HMGCS2 anticorps

Épitope: AA 478-508, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This HMGCS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 478-508 amino acids from the C-terminal region of human HMGCS2.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-HMGCS2 (ABIN390764)

Huang, Li, Wang, Zhang, Yan, Li, Xing, Wu, Hu, Jia, Lin, Dang, Song, Gao, Zhang: "Hepatocellular carcinoma redirects to ketolysis for progression under nutrition deprivation stress." dans: Cell research, Vol. 26, Issue 10, pp. 1112-1130, (2017) (PubMed).

Détails sur HMGCS2

Antigène: HMGCS2 (3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2))

Autre désignation: HMGCS2

Sujet: HMGCS2 belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting.

Poids moléculaire: 56635

ID gène: 3158

NCBI Accession: NP_001159579, NP_005509

UniProt: P54868

Pathways: Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha