PKM2 anticorps (N-Term)

N° du produit ABIN391052

L’anticorps Lapin Polyclonal anti-PKM2 a été validé pour WB. Il convient pour détecter PKM2 dans des échantillons de Humain et Souris. Il y a 1 publication disponible.

Aperçu rapide pour PKM2 anticorps (N-Term) (ABIN391052)

Antigène: PKM2 (Pyruvate Kinase M2 (PKM2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PKM2 est non-conjugé

Application: Western Blotting (WB)

Clone: RB5870

Détail du produit anti-PKM2 anticorps

Épitope: AA 121-151, N-Term

Homologie: Rb, Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This Pyruvate Kinase (PKM2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 121-151 amino acids from the N-terminal region of human Pyruvate Kinase (PKM2).

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000. WB: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-PKM2 (ABIN391052)

Shin, Yoo, Hong, Chang, Jung, Jeong, Park: "Upregulation of glycolytic enzymes in proteins secreted from human colon cancer cells with 5-fluorouracil resistance." dans: Electrophoresis, Vol. 30, Issue 12, pp. 2182-92, (2009) (PubMed).

Détails sur PKM2

Antigène: PKM2 (Pyruvate Kinase M2 (PKM2))

Autre désignation: Pyruvate Kinase (PKM2)

Sujet: PKM2 is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. This protein has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.

Poids moléculaire: 57937

ID gène: 5315

NCBI Accession: NP_001193725, NP_001193726, NP_001193727, NP_001193728, NP_002645, NP_872270, NP_872271

UniProt: P14618

Pathways: L'effet Warburg