PKM2 anticorps (C-Term)

N° du produit ABIN391053

Cet anticorps anti-PKM2 est un anticorps Lapin Polyclonal détectant PKM2 dans WB, IHC (p) et IF. Adapté pour Humain, Souris, Rat et Singe. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour PKM2 anticorps (C-Term) (ABIN391053)

Antigène: PKM2 (Pyruvate Kinase M2 (PKM2))

Reactivité: Humain, Souris, Rat, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PKM2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Clone: RB3697

Détail du produit anti-PKM2 anticorps

Épitope: AA 476-505, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This Pyruvate Kinase (PKM2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 476-505 amino acids from the C-terminal region of human Pyruvate Kinase (PKM2).

Isotype: Ig Fraction

Information d'application

Indications d'application: IF: 1:200. WB: 1:1000. WB: 1:1000. WB: 1:2000. IHC-P: 1:50~1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze-thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

Date de péremption: 6 months

Références pour anticorps anti-PKM2 (ABIN391053)

Kienzl, Sarg, Golderer, Obrist, Werner, Werner-Felmayer, Lindner, Maglione, Schneeberger, Margreiter, Brandacher: "Proteomic profiling of acute cardiac allograft rejection." dans: Transplantation, Vol. 88, Issue 4, pp. 553-60, (2009) (PubMed).

Détails sur PKM2

Antigène: PKM2 (Pyruvate Kinase M2 (PKM2))

Autre désignation: PKM2

Sujet: There are 4 isozymes of pyruvate kinase in mammals: L, R, M1 and M2. PKM2 is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. This protein has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.

Poids moléculaire: 57937

ID gène: 5315

NCBI Accession: NP_001193725, NP_001193726, NP_001193727, NP_001193728, NP_002645, NP_872270, NP_872271

UniProt: P14618

Pathways: L'effet Warburg