CLASP2 anticorps (C-Term)

N° du produit ABIN391268

L’anticorps anti-CLASP2 Polyclonal Lapin est utilisé pour la détection de CLASP2 dans des échantillons de Humain. Il a été validé pour WB et IHC (p).

Aperçu rapide pour CLASP2 anticorps (C-Term) (ABIN391268)

Antigène: CLASP2 (Cytoplasmic Linker Associated Protein 2 (CLASP2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CLASP2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB9127

Détail du produit anti-CLASP2 anticorps

Épitope: AA 946-975, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This CLASP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 946-975 amino acids from the C-terminal region of human CLASP2.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur CLASP2

Antigène: CLASP2 (Cytoplasmic Linker Associated Protein 2 (CLASP2))

Autre désignation: CLASP2

Sujet: Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.

Poids moléculaire: 141064

ID gène: 23122

NCBI Accession: NP_001193973, NP_055912

UniProt: O75122

Pathways: Dynamique des Microtubules, Maintenance of Protein Location