CLASP2 anticorps (AA 226-381)

N° du produit ABIN7147936

Détail du produit anti-CLASP2 anticorps

Antigène: CLASP2 (Cytoplasmic Linker Associated Protein 2 (CLASP2))

Épitope: AA 226-381

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CLASP2 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human CLIP-associating protein 2 protein (226-381AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200, IP:1:200-1:2000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CLASP2

Antigène: CLASP2 (Cytoplasmic Linker Associated Protein 2 (CLASP2))

Autre désignation: CLASP2 (CLASP2 Produits)

Synonymes: anticorps zgc:77279, anticorps DKFZp459M112, anticorps 1500004F14Rik, anticorps 8030404L10Rik, anticorps C77448, anticorps CLASP2beta, anticorps mKIAA0627, anticorps cytoplasmic linker associated protein 2, anticorps CLIP associating protein 2, anticorps clasp2, anticorps CLASP2, anticorps Clasp2

Sujet:

Background: Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules (PubMed:26003921). Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2 (PubMed:16824950). This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle (PubMed:16866869, PubMed:16914514). Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex.

Aliases: CLAP2_HUMAN antibody, CLASP 2 antibody, Clasp2 antibody, CLIP associating protein 2 antibody, CLIP-associating protein 2 antibody, Cytoplasmic linker associated protein 2 antibody, Cytoplasmic linker-associated protein 2 antibody, hOrbit2 antibody, KIAA0627 antibody, Multiple asters (Mast) like homolog 2 antibody, Protein Orbit homolog 2 antibody

UniProt: O75122

Pathways: Dynamique des Microtubules, Maintenance of Protein Location