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RIPK3 anticorps (N-Term)

RIPK3 Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal RB8631 unconjugated
N° du produit ABIN391272
  • Antigène Voir toutes RIPK3 Anticorps
    RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))
    Épitope
    • 11
    • 8
    • 8
    • 7
    • 7
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-30, N-Term
    Reactivité
    • 79
    • 43
    • 19
    • 6
    • 4
    • 4
    • 2
    • 1
    Humain
    Hôte
    • 82
    • 9
    Lapin
    Clonalité
    • 82
    • 9
    Polyclonal
    Conjugué
    • 46
    • 9
    • 8
    • 7
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp RIPK3 est non-conjugé
    Application
    • 84
    • 52
    • 44
    • 18
    • 11
    • 8
    • 6
    • 5
    • 4
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogène
    This RIPK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human RIPK3.
    Clone
    RB8631
    Isotype
    Ig Fraction
    Top Product
    Discover our top product RIPK3 Anticorps primaire
  • Indications d'application
    WB: 1:1000. IHC-P: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Viringipurampeer, Metcalfe, Bashar, Sivak, Yanai, Mohammadi, Moritz, Gregory-Evans, Gregory-Evans: "NLRP3 inflammasome activation drives bystander cone photoreceptor cell death in a P23H rhodopsin model of retinal degeneration." dans: Human molecular genetics, Vol. 25, Issue 8, pp. 1501-16, (2016) (PubMed).

    Viringipurampeer, Ferreira, DeMaria, Yoon, Shan, Moosajee, Gregory-Evans, Ngai, Gregory-Evans: "Pax2 regulates a fadd-dependent molecular switch that drives tissue fusion during eye development." dans: Human molecular genetics, Vol. 21, Issue 10, pp. 2357-69, (2012) (PubMed).

  • Antigène
    RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))
    Autre désignation
    RIPK3 (RIPK3 Produits)
    Synonymes
    anticorps RIPK3, anticorps RIP3, anticorps 2610528K09Rik, anticorps AW107945, anticorps Rip3, anticorps Hcyp2, anticorps receptor interacting serine/threonine kinase 3, anticorps receptor interacting serine/threonine kinase 3 S homeolog, anticorps receptor-interacting serine-threonine kinase 3, anticorps RIPK3, anticorps ripk3.S, anticorps Ripk3
    Sujet
    The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.
    Poids moléculaire
    56887
    ID gène
    11035
    NCBI Accession
    NP_006862
    UniProt
    Q9Y572
    Pathways
    Activation of Innate immune Response, Toll-Like Receptors Cascades
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