DAP Kinase 1 anticorps (C-Term)
Aperçu rapide pour DAP Kinase 1 anticorps (C-Term) (ABIN2841351)
Antigène
Voir toutes DAP Kinase 1 (DAPK1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 1360-1389, C-Term
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Purification
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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Immunogène
- This DAPK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1360-1389 amino acids from the C-terminal region of human DAPK1.
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Isotype
- Ig Fraction
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Indications d'application
- IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Date de péremption
- 6 months
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: "Silencing DNA methyltransferase 1 (DNMT1) inhibits proliferation, metastasis and invasion in ESCC by suppressing methylation of RASSF1A and DAPK." dans: Oncotarget, Vol. 7, Issue 28, pp. 44129-44141, (2018) (PubMed).
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- DAP Kinase 1 (DAPK1) (Death-Associated Protein Kinase 1 (DAPK1))
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Autre désignation
- DAP Kinase 1 (DAPK1)
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Sujet
- Death-associated protein kinase 1 is a positive mediator of gamma-interferon induced programmed cell death (apoptosis). DAPK1 encodes a structurally unique 160-kD calmodulin dependent serine-threonine kinase that carries 8 ankyrin repeats and 2 putative P-loop consensus sites. It is a tumor suppressor candidate.
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Poids moléculaire
- 160046
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ID gène
- 1612
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NCBI Accession
- NP_004929
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UniProt
- P53355
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Pathways
- Signalisation MAPK, Interferon-gamma Pathway
Antigène
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