Prohibitin 2 anticorps (AA 225-255)

N° du produit ABIN391413

Cet anticorps anti-Prohibitin 2 est un anticorps Lapin Polyclonal détectant Prohibitin 2 dans WB et IHC (p). Adapté pour Humain et Souris.

Aperçu rapide pour Prohibitin 2 anticorps (AA 225-255) (ABIN391413)

Antigène: Prohibitin 2 (PHB2)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Prohibitin 2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB15576

Détail du produit anti-Prohibitin 2 anticorps

Épitope: AA 225-255

Homologie: B, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This PHB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 225-255 amino acids from human PHB2.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P-Leica: 1:500. IHC-P-Leica: 1:250. IHC-P-Leica: 1:250

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur Prohibitin 2

Antigène: Prohibitin 2 (PHB2)

Autre désignation: PHB2

Sujet: PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases. It functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. It competes with NCOA1 for modulation of ER transcriptional activity and is probably involved in regulating mitochondrial respiration activity and in aging.

Poids moléculaire: 33296

ID gène: 11331

NCBI Accession: NP_001138303, NP_001254629

UniProt: Q99623

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling