NAE1 anticorps (C-Term)

N° du produit ABIN391418

L’anticorps Lapin Polyclonal anti-NAE1 a été validé pour WB et IHC (p). Il convient pour détecter NAE1 dans des échantillons de Humain.

Aperçu rapide pour NAE1 anticorps (C-Term) (ABIN391418)

Antigène: NAE1 (NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NAE1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB8977

Détail du produit anti-NAE1 anticorps

Épitope: AA 430-459, C-Term

Homologie: Pr, M, Rat

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogène: This NAE1 (APPBP1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 430-459 amino acids from the C-terminal region of human NAE1 (APPBP1).

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur NAE1

Antigène: NAE1 (NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))

Autre désignation: NAE1 (APPBP1)

Sujet: APPBP1 binds to the beta-amyloid precursor protein, a cell surface protein with signal-transducing properties thought to play a role in the pathogenesis of Alzheimer's disease. In addition, this protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. APPB1 is required for cell cycle progression through the S/M checkpoint.

Poids moléculaire: 60246

ID gène: 8883

NCBI Accession: NP_001018169, NP_001018170, NP_003896

UniProt: Q13564