CLK2 anticorps (N-Term)

N° du produit ABIN391766

Il existe 2+ publications pour ce produit. L’anticorps anti-CLK2 Polyclonal Lapin est utilisé pour la détection de CLK2 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour CLK2 anticorps (N-Term) (ABIN391766)

Antigène: CLK2 (CDC-Like Kinase 2 (CLK2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CLK2 est non-conjugé

Application: Western Blotting (WB)

Clone: RB3205

Détail du produit anti-CLK2 anticorps

Épitope: AA 1-30, N-Term

Homologie: M

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This CLK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CLK2.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-CLK2 (ABIN391766)

Yoshida, Kim, Carver, Su, Weremowicz, Mulvey, Yamamoto, Brennan, Mei, Long, Yao, Polyak: "CLK2 Is an Oncogenic Kinase and Splicing Regulator in Breast Cancer." dans: Cancer research, Vol. 75, Issue 7, pp. 1516-26, (2015) (PubMed).

Nam, Seo, Park, An, Kim, Yang, Kim, Jeong, Jin: "Phosphorylation of CLK2 at serine 34 and threonine 127 by AKT controls cell survival after ionizing radiation." dans: The Journal of biological chemistry, Vol. 285, Issue 41, pp. 31157-63, (2010) (PubMed).

Détails sur CLK2

Antigène: CLK2 (CDC-Like Kinase 2 (CLK2))

Autre désignation: CLK2

Sujet: This gene encodes a member of the CLK family of dual specificity protein kinases. CLK family members have shown to interact with, and phosphorylate, serine- and arginine-rich (SR) proteins of the spliceosomal complex, which is a part of the regulatory mechanism that enables the SR proteins to control RNA splicing. This protein kinase is involved in the regulation of several cellular processes and may serve as a link between cell cycle progression, apoptosis, and telomere length regulation.

Poids moléculaire: 60090

ID gène: 1196

NCBI Accession: NP_003984

UniProt: P49760

Pathways: Regulation of Carbohydrate Metabolic Process