HIPK3 anticorps (C-Term)
Aperçu rapide pour HIPK3 anticorps (C-Term) (ABIN391779)
Antigène
Voir toutes HIPK3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 1127-1156, C-Term
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Homologie
- M, Rat
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This HIPK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1127-1156 amino acids from the C-terminal region of human HIPK3.
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Isotype
- Ig Fraction
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Indications d'application
- WB: 1:2000. WB: 1:1000. IHC-P: 1:25
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Date de péremption
- 6 months
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: "Death-associated protein 6 (Daxx) mediates cAMP-dependent stimulation of Cyp11a1 (P450scc) transcription." dans: The Journal of biological chemistry, Vol. 287, Issue 8, pp. 5910-6, (2012) (PubMed).
: "A live zebrafish-based screening system for human nuclear receptor ligand and cofactor discovery." dans: PLoS ONE, Vol. 5, Issue 3, pp. e9797, (2010) (PubMed).
: "Cyclic AMP stimulates SF-1-dependent CYP11A1 expression through homeodomain-interacting protein kinase 3-mediated Jun N-terminal kinase and c-Jun phosphorylation." dans: Molecular and cellular biology, Vol. 27, Issue 6, pp. 2027-36, (2007) (PubMed).
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- HIPK3 (Homeodomain Interacting Protein Kinase 3 (HIPK3))
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Autre désignation
- HIPK3
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Sujet
- HIPK3 negatively regulates apoptosis by promoting FADD phosphorylation. This kinase enhances androgen receptor-mediated transcription, and may act as a transcriptional corepressor for NK homeodomain transcription factors.
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Poids moléculaire
- 133743
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ID gène
- 10114
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NCBI Accession
- NP_001041665, NP_001265091, NP_001265092, NP_005725
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UniProt
- Q9H422
Antigène
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