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EPH Receptor A2 anticorps (N-Term)

EPHA2 Reactivité: Humain, Souris WB, FACS, IHC (p) Hôte: Lapin Polyclonal RB01579 unconjugated
N° du produit ABIN391885
  • Antigène Voir toutes EPH Receptor A2 (EPHA2) Anticorps
    EPH Receptor A2 (EPHA2)
    Épitope
    • 19
    • 15
    • 15
    • 15
    • 10
    • 10
    • 9
    • 9
    • 9
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 30-60, N-Term
    Reactivité
    • 183
    • 128
    • 70
    • 14
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 191
    • 19
    • 4
    • 1
    • 1
    Lapin
    Clonalité
    • 188
    • 27
    • 1
    Polyclonal
    Conjugué
    • 74
    • 20
    • 12
    • 12
    • 12
    • 12
    • 12
    • 12
    • 11
    • 10
    • 10
    • 9
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp EPH Receptor A2 est non-conjugé
    Application
    • 131
    • 80
    • 28
    • 27
    • 21
    • 14
    • 12
    • 8
    • 7
    • 7
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    Pr
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogène
    This EphA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-60 amino acids from the N-terminal region of human EphA2.
    Clone
    RB01579
    Isotype
    Ig Fraction
  • Indications d'application
    WB: 1:1000. WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Tatsukawa, Koga, Aoki, Koshikawa, Imafuku, Nakayama, Nabeshima: "Immunohistochemical demonstration of EphA2 processing by MT1-MMP in invasive cutaneous squamous cell carcinoma." dans: Virchows Archiv : an international journal of pathology, Vol. 469, Issue 1, pp. 25-34, (2017) (PubMed).

  • Antigène
    EPH Receptor A2 (EPHA2)
    Autre désignation
    EphA2 (EPHA2 Produits)
    Synonymes
    anticorps ARCC2, anticorps CTPA, anticorps CTPP1, anticorps CTRCT6, anticorps ECK, anticorps epha2, anticorps MGC89505, anticorps AW545284, anticorps Eck, anticorps Myk2, anticorps Sek-2, anticorps Sek2, anticorps id:ibd5152, anticorps rtk6, anticorps G42, anticorps XE10, anticorps epha2-A, anticorps EPH receptor A2, anticorps Eph receptor A2, anticorps epoxide hydrolase, anticorps eph receptor A2 a, anticorps EPH receptor A2 L homeolog, anticorps EPHA2, anticorps Epha2, anticorps epha2, anticorps ephA2, anticorps epha2a, anticorps epha2.L
    Sujet
    Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).
    Poids moléculaire
    108266
    ID gène
    1969
    NCBI Accession
    NP_004422
    UniProt
    P29317
    Pathways
    Signalisation RTK
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