EPH Receptor B1 anticorps (C-Term)

N° du produit ABIN391917

Cet anticorps anti-EPH Receptor B1 est un anticorps Lapin Polyclonal détectant EPH Receptor B1 dans WB et IHC (p). Adapté pour Humain et Souris. Ce Primary Antibody a été cité dans 2+ publications.

Aperçu rapide pour EPH Receptor B1 anticorps (C-Term) (ABIN391917)

Antigène: EPH Receptor B1 (EPHB1)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EPH Receptor B1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB1648

Détail du produit anti-EPH Receptor B1 anticorps

Épitope: AA 955-984, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This EphB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 955-984 amino acids from the C-terminal region of human EphB1.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-EPH Receptor B1 (ABIN391917)

Sheng, Wang, Dong, Ma, Zhou, Sugimura, Lu, Zhou: "EphB1 is underexpressed in poorly differentiated colorectal cancers." dans: Pathobiology : journal of immunopathology, molecular and cellular biology, Vol. 75, Issue 5, pp. 274-80, (2008) (PubMed).

Wang, Dong, Sheng, Ma, Li, Wang, Lu, Sugimura, Jin, Zhou: "Loss of expression of EphB1 protein in gastric carcinoma associated with invasion and metastasis." dans: Oncology, Vol. 73, Issue 3-4, pp. 238-45, (2008) (PubMed).

Détails sur EPH Receptor B1

Antigène: EPH Receptor B1 (EPHB1)

Autre désignation: EphB1

Sujet: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).

Poids moléculaire: 109885

ID gène: 2047

NCBI Accession: NP_004432

UniProt: P54762

Pathways: Signalisation RTK