TEK anticorps (C-Term)
Aperçu rapide pour TEK anticorps (C-Term) (ABIN392059)
Antigène
Voir toutes TEK AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Épitope
- AA 758-789, C-Term
-
Homologie
- B
-
Purification
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
-
Immunogène
- This TEK (TIE2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 758-789 amino acids from the C-terminal region of human TEK (TIE2).
-
Isotype
- Ig Fraction
-
-
-
-
Indications d'application
- WB: 1:1000. IHC-P: 1:50~100. IHC-P: 1:50~100
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
Date de péremption
- 6 months
-
-
- TEK (TEK Tyrosine Kinase, Endothelial (TEK))
-
Autre désignation
- TEK (TIE2)
-
Sujet
- The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations, the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase.
-
Poids moléculaire
- 125830
-
ID gène
- 7010
-
NCBI Accession
- NP_000450
-
UniProt
- Q02763
-
Pathways
- Signalisation RTK, Growth Factor Binding
Antigène
-